HELPING THE OTHERS REALIZE THE ADVANTAGES OF BREFELDIN A

lumacaftor/ivacaftor will reduce the level or influence of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers lowers plasma concentration of abemaciclib and its metabolites.Cell proliferation was assessed employing a bromodeoxyuridine (BrdU